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Circulatory System Simulation TeamSoft and Hard Tissue Simulation TeamHuman Motion Simulation Team
Research
Soft and Hard Tissue Simulation Team
Hard Tissue Simulation Soft Tissue Simulation>>
The hard tissue simulation group has constructed a simulation model that reproduces bone remodeling caused by the mechanical stimulation on the bone.
In addition, based on the simulator that reproduces the remodeling, the group investigated other applications for the simulation of conformational change of bones after the insertion of an implant, the design system of the implant, and the scaffold design for regeneration medicine.
The research has been conducted according to the following framework.
The overview and the overall flow are described here.
Please refer to the linked pages for the details.

1. Simulator development of bone remodeling
The development of a simulator that can reproduce the remodeling occurring in the cancellous region within a bone was conducted. As shown in the left column of the figure on the right, researches regarding “the acquirement of conformational data of bone structure,” “the acquirement of bone material data,” “the experimental investigation of bone remodeling mechanism,” “the simulation method of trabecular bone remodeling,” “the development of a large-scale simulation method for trabecular bone remodeling,” and “micro-macro coupled simulation of trabecular bone remodeling” were conducted. This was followed by the successful construction of a simulator that can reproduce the trabecular bone structure inside the human femur. Please refer to the linked pages (--> Kenichi Tsubota’s pages) for further details.


2. Design of implant conformation and development of a simulator for bone regeneration process
Based on the abovementioned simulator model, further research aimed at developing a conformation design of an implant intended to be inserted into the bone and simulating bone regeneration after the damage has been imposed. Please refer to the linked pages (--> Taiji Adachi's pages) for further details.

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